Charleston, SC was where Dr. Lyles began her career as a Doctor of Chiropractic. Living and working in the downtown community, Dr. Lyles established her practice through educational seminars and public speaking engagements. Likewise, she networked through clubs and organizations such as the Charitable Society of Charleston, Charleston Association of Female Entrepreneurs, and Junior Achievement. Companies such as Bell South, Trident Technical College, Federally Employed Women, City of Charleston Public Service Employees, South Trust Bank, and Charleston Public Waterworks relied on Dr. Lyles to educate their employees on topics such as ergonomics and proper lifting, stress reduction and nutrition, Carpal Tunnel Syndrome, and spinal hygiene. As a business partner of local schools, Dr. Lyles often attended PTA meetings as a guest speaker, discussing topics such as scoliosis and backpack safety, offering complimentary screenings.

A former athlete, Dr. Lyles gravitated toward learning more about care of the extremities to compliment her care of the spine. She traveled around the country, attending advanced seminars on the shoulder, wrist, hand, hip, knee, ankle and foot.  While in Charleston, she worked with rugby and basketball players at the College of Charleston, and was asked to attend a championship soccer tournament in Kingston, Jamaica as the team Chiropractor.

After four and a half years in Charleston, Dr. Lyles missed the opportunities that a big city could offer; she returned to Atlanta to embark on a new journey as an educator, a passion of Dr. Lyles'. After two years as an Assistant Professor in Clinical Education, Dr. Lyles was asked to be the Clinic Director of the largest Chiropractic College in the world! She accepted and managed to also maintain a part-time practice. For community service, she served on Atlanta Falcon (#20) Allen Rossum’s Board of Directors for his Healthy Kids Klub created to fight childhood obesity.